Niacinamide, the key for high NAD+, testosterone, DHT and sexual function… Are NMN and NR ripoffs if you could just use niacinamide? Let’s talk about the benefits of niacinamide! Niacinamide on testosterone At least 3 steroidogenic enzymes use NAD+. This includes CYP450scc (cholesterol side chain cleavage enzyme), 3β-HSD and 17β-HSD3. Supplementing rats with niacinamide reduced … Read more
Serotonin (in excess) can lower testosterone. Should we thus avoid food high in serotonin if our goal is to maximize testosterone? Quick background on serotonin Serotonin is produced from tryptophan via the enzymes tryptophan hydroxylase (TPH) 1 & 2. About 90-95% of all serotonin is produced in the gut and the remaining 5-10% is produced … Read more
Serotonin is synonymous with sleep. The misconception that serotonin promotes sleep is as strong as the dubious claim that serotonin is the “happiness” hormone. Want to sleep better? Boost your serotonin. But does it really help? What if it actually does the opposite? What sleep looks like There are typically four to six cycles of … Read more
Meh! That’s your brain in serotonin. Do you want to run away from your emotions, or still have emotions? SSRIs are one of the most common prescribed class of drugs for almost any kind of mental condition. Feeling a bit off today? Here an SSRI! It’s like house of Oprah. Although SSRI are helpful for … Read more
How does stable mood, good energy, mental clarity and good deep sleep sound to you? And those are not the only benefits you’ll get from lower serotonin, but also less inflammation, between circulation, stronger bones, higher testosterone and dopamine, better sex drive and sexual health and so much more. Serotonin is a stress hormone that … Read more
Depression makes you feel like: “Life is a “beach”. Life just sucks, or so it feels. Major depressive disorder (MDD) is one of the oldest well-recognized medical disorders, having been clearly described in medical texts dating back to ancient Greece. Depression is a stress-related disorder that includes abnormalities of affect and mood, neurogenerative functions (such … Read more
Most of us have that drive to push ourselves hard each workout. We try to go “all out” each workout.We have to demolish the PRs of the previous workouts, right? And so we do everything possible to squeeze every bit out of our training. But is this the right thing to do?It sure feels like … Read more
For the past decades white lies and muddied research established serotonin as a beneficial neurotransmitter for mental and physical health. However, more and more research, that reveals the truth about serotonin, is starting to surface and topple that muddy tower of serotonin “goodness” down. Serotonin is turning out to be much more of a downer … Read more
Serotonin is a complicated neurotransmitter that, contrary to other neurotransmitters, has an influence on everything in the body. It’s currently believed to aid in anxiety, depression, impatience, impulsiveness, anger, etc. One of the main reasons for this is that the metabolite of serotonin, 5-HIAA, is low in people with these symptoms. The research is thus … Read more
Serotonin is synthesized in both the brain as well as in the gut, but for this article, I’m just going to focus on the serotonin in the brain as it influences how you feel mentally and determines certain behaviors. Whereas gut serotonin doesn’t have the same effect because it cannot cross the blood-brain barrier, meaning … Read more